Callaghan Neal, Hadipour-Lakmehsari Sina, Lee Shin-Haw, Gramolini Anthony O., Simmons Craig A., Modeling cardiac complexity: Advancements in myocardial models and analytical techniques for physiological investigation and therapeutic development in vitro. APL Bioengineering. 2019 | AIP
Zhang Xiaoqing, Battiston Kyle, Simmons Craig A, Santerre J Paul. Differential regulation of extracellular matrix components by using different vitamin C derivatives in mono-and co-culture systems. ACS Biomaterials Science & Engineering. 2017 | ACS
Zhang Xiaoqing, Battiston Kyle G, Labow Rosalind S, Simmons Craig A,Santerre J Paul. Generating favorable growth factor and protease release profiles to enable extracellular matrix accumulation within an in vitro tissue engineering environment. Acta Biomaterialia. 2017;54:81-84 | PubMed
Wen Jun, Tao Hirotaka, Lau Kimberly, Liu Haijiao, Simmons Craig A, Sun Yu, Hopyan Sevan. Cell and Tissue Scale Forces Coregulate Fgfr2-Dependent Tetrads and Rosettes in the Mouse Embryo. Biophysical Journal. 2017;112(10):2209-2218. | PubMed
Zhang Xiaoqing, Bendeck Michelle P, Simmons Craig A, Santerre, J Paul. Deriving vascular smooth muscle cells from mesenchymal stromal cells: Evolving differentiation strategies and current understanding of their mechanisms. Biomaterials; 2017;145:9-22 | PubMed
Safaee Helia, Bakooshli Mohsen A, Davoudi Sadegh, Cheng, Richard Y, Martowirogo Aditya J, Li Edward W, Simmons Craig A, Gilbert, Penney M. Tethered Jagged-1 Synergizes with Culture Substrate Stiffness to Modulate Notch-Induced Myogenic Progenitor Differentiation. Cellular and molecular bioengineering. 2017;10(5):501-513. | SpringerLink
Usprech Jenna, Romero David A, Amon Cristina H, Simmons Craig A. Combinatorial screening of 3D biomaterial properties that promote myofibrogenesis for mesenchymal stromal cell-based heart valve tissue engineering. Acta Biomaterialia. 2017;58:34-43. | PubMed
Loai S, Haedicke I, Mirzaei Z, Simmons CA, Zhang XA, Cheng HL. Positive-contrast cellular MRI of embryonic stem cells for tissue regeneration using a highly efficient T1 MRI contrast agent. J Magn Reson Imaging, 2016; 44:1456-1463| PubMed
Ireland R, Simmons CA. Pluripotent stem cell mechanobiology. Stem Cells (invited review), 2015;33:3187-96. | PubMed
Battiston KG, Ouyang B, Honarparvar E, Qian J, Labow RS, Simmons CA, Santerre JP. Interaction of a block-co-polymeric biomaterial with immunoglobulin G modulates human monocytes towards a non-inflammatory phenotype. Acta Biomaterialia, 2015; 24:35-43. | PubMed
Battiston KG, Ouyang B, Labow RS, Simmons CA, Santerre JP. Using monocytes/macrophages and their cytokine activity to promote vascular smooth muscle cell growth on a degradable polyurethane scaffold. Acta Biomaterialia, 2014;10:1146-55. | PubMed
Battiston KG, Ouyang B, Labow RS, Simmons CA, Santerre JP. Using monocytes/macrophages and their cytokine activity to promote vascular smooth muscle cell growth on a degradable polyurethane scaffold. Acta Biomaterialia, 2014;10:1146-55.| PubMed
Thavandiran N, Dubois N, Mikryukov A, Masse S, Beca B, Simmons CA, Deshpande V, McGarry P, Chen CS, Nanthakumar K, Keller G, Radisic M, Zandstra PW. Design and formulation of functional pluripotent stem cell-derived cardiac microtissues. Proc Natl Acad Sci U S A, 2013;110:E4698-707.| PubMed
Cheung WY, Simmons CA#, You L#. Osteocyte apoptosis regulates osteoclast precursor adhesion via osteocytic IL-6 secretion and endothelial ICAM-1 expression. Bone, 2012;50:104-110.| PubMed
Yip CY, Blaser MC, Mirzaei Z, Zhong X, Simmons CA. Inhibition of pathological differentiation of valve interstitial cells by C-type natriuretic peptide. Arterioscler Thromb Vasc Biol, 2011;31:1881-1889. Supplemental material| PubMed
Chen JH, Chen WLK, Sider KL, Yip CYY and Simmons CA. β-catenin mediates mechanically regulated, transforming growth factor-β1 induced myofibroblast differentiation of aortic valve interstitial cells. Arterioscler Thromb Vasc Biol, 2011;31:590-597.Supplemental material / Commentary| PubMed
Yuen A, Laschinger C, Talior I, Lee W, Chan M, Birek J, Young EWK, Sivagurunathan K, Won E, Simmons CA, McCulloch CA. Methylglyoxal-modified collagen promotes myofibroblast differentiation. Matrix Biology, 2010;29:537-48. | PubMed
Bhana B, Iyer RK, Chen WL, Zhao R, Sider KL, Likhitpanichkul M, Simmons CA, Radisic M. Influence of substrate stiffness on the phenotype of heart cells. Biotechnol Bioeng, 2010;105:1148-1160. Journal cover| PubMed
Rask F*, Mihic A*, Reis L, Dallabrida SM, Ismail NS, Sider KL, Simmons CA, Rupnick MA, Weisel RD, Li R, Radisic M. Hydrogels modified with QHREDGS peptide support cardiomyocyte survival in vitro and after sub-cutaneous implantation. Soft Matter,2010;95:105-117.| PubMed
Brooks PJ, Nilforoushan D, Manolson MF, Simmons CA, Gong S-G. Molecular markers of early orthodontic tooth movement.Angle Orthod, 2009; 79:1108-1113.| PubMed
Pho M, Lee W, Watt DR, Laschinger C, Simmons CA, McCulloch CA. Cofilin is a marker of myofibroblast differentiation in cells from porcine aortic cardiac valves. Am J Physiol Heart Circ, 2008;294:H1767-1778.| PubMed
Huang YC, Simmons CA, Kaigler D, Rice KG, Mooney DJ. Bone regeneration in a rat cranial defect with delivery of PEI-condensed plasmid DNA encoding for bone morphogenetic protein-4 (BMP-4). Gene Ther, 2005;12:418-426.| PubMed
Murphy WL, Hsiong S, Richardson TP, Simmons CA, Mooney DJ. Effects of a bone-like mineral film on phenotype of adult human mesenchymal stem cells in vitro. Biomaterials, 2005; 26:303-310.| PubMed
Simmons CA, Alsberg E, Hsiong S, Kim WJ, Mooney DJ. Dual growth factor delivery and controlled scaffold degradation enhance in vivo bone formation by transplanted bone marrow stromal cells. Bone, 2004;35:562-569.| PubMed
Murphy WL*, Simmons CA*, Kaigler D, Mooney DJ. Bone regeneration via a mineral substrate and induced angiogenesis. J Dent Res, 2004;83:204-210.| PubMed
Simmons CA, Matlis S, Thornton AJ, Chen S, Wang CY, Mooney DJ. Cyclic strain enhances matrix mineralization by adult human mesenchymal stem cells via the extracellular signal-regulated kinase (ERK1/2) signaling pathway. J Biomech,2003;36:1087-1096.| PubMed