Overview
The Simmons lab investigates how biomechanical forces on cells lead to regeneration, repair, and disease of cardiovascular tissues. Our dynamic team of engineers, biomedical scientists, and physicists tackle applied biomedical problems in the areas of heart valve mechanobiology and disease, stem cell-based tissue regeneration, and microfluidic physiological systems. We are affiliated with the Department of Mechanical & Industrial Engineering and Institute of Biomaterials & Biomedical Engineering at the University of Toronto, and are core members of the Translational Biology & Engineering Program in the Ted Rogers Centre for Heart Research.

Recent News

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Recent Publications

  • Sefton Michael V, Simmons Craig A. Hearts by design. Science | AAAS

  • Dou Wenkun, Malhi Manpreet, Cui Teng, Wang Minyao, Wang Tiancong, Shan Guanqiao, Law Junhui, Gong Zheyuan, Plakhotnik Julia, Filleter Tobin, Li Renke, Simmons Craig A., Maynes Jason T., Sun Yu. A carbon-based biosensing platform for simultaneously measuring the contraction and electrophysiology of iPSC-cardiomyocyte monolayers. ACS Nano. 2022 | American Chemical Society

  • Wong Edwin KY., Parvin Nejad Shouka, D’Costa Katya A., Machado Siqueira Nataly, Lecce Monica, Santerre Paul, Simmons Craig A. Design of a mechanobioreactor to apply anisotropic, biaxial strain to large thin biomaterials for tissue engineered heart valve applications. Annals of Biomedical Engineering. 2022 | Springer

More publications

The Simmons lab investigates how biomechanical forces on cells lead to regeneration, repair, and disease of cardiovascular tissues. Our dynamic team of engineers, biomedical scientists, and physicists tackle applied biomedical problems in the areas of heart valve mechanobiology and disease, stem cell-based tissue regeneration, and microfluidic physiological systems. We are affiliated with the Department of Mechanical & Industrial Engineering and Institute of Biomaterials & Biomedical Engineering at the University of Toronto, and are core members of the Translational Biology & Engineering Program in the Ted Rogers Centre for Heart Research.

Recent News

More news

Recent Publications

  • Sefton Michael V, Simmons Craig A. Hearts by design. Science | AAAS

    Continue reading →

  • Dou Wenkun, Malhi Manpreet, Cui Teng, Wang Minyao, Wang Tiancong, Shan Guanqiao, Law Junhui, Gong Zheyuan, Plakhotnik Julia, Filleter Tobin, Li Renke, Simmons Craig A., Maynes Jason T., Sun Yu. A carbon-based biosensing platform for simultaneously measuring the contraction and electrophysiology of iPSC-cardiomyocyte monolayers. ACS Nano. 2022 | American Chemical Society

    Continue reading →

  • Wong Edwin KY., Parvin Nejad Shouka, D’Costa Katya A., Machado Siqueira Nataly, Lecce Monica, Santerre Paul, Simmons Craig A. Design of a mechanobioreactor to apply anisotropic, biaxial strain to large thin biomaterials for tissue engineered heart valve applications. Annals of Biomedical Engineering. 2022 | Springer

    Continue reading →

More publications