Overview
The Simmons lab investigates how biomechanical forces on cells lead to regeneration, repair, and disease of cardiovascular tissues. Our dynamic team of engineers, biomedical scientists, and physicists tackle applied biomedical problems in the areas of heart valve mechanobiology and disease, stem cell-based tissue regeneration, and microfluidic physiological systems. We are affiliated with the Department of Mechanical & Industrial Engineering and Institute of Biomaterials & Biomedical Engineering at the University of Toronto, and are core members of the Translational Biology & Engineering Program in the Ted Rogers Centre for Heart Research.

Recent News

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Recent Publications

  • Anthonyshyn Jeremy A., Mazzoli Vienna, McFadden Meghan J., Gramolini Anthony O., Hofer Stefan O. P., Simmons Craig A., Santerre, Paul. Mitigating the non-specific uptake of immunomagnetic microparticles enables the extraction of endothelium from human fat. Communications Biology. 2021 | Nature Publishing Group

  • Tang Mingyi, Eliathamby Daniella, Ouzounian Maral, Simmons Craig A, Chung Jennifer C.-Y. Dependency of energy loss on strain rate, strain magnitude and preload: Towards development of a novel biomarker for aortic aneurysm dissection risk. Journal of the Mechanical Behavior of Biomedical Materials. 2021 | Elsevier

  • Liu Haijao, Usprech Jenna F., Parameshwar Prabu K., Sun Yu, Simmons Craig A. Combinatorial screen of dynamic mechanical stimuli for predictive control of MSC mechano-responsiveness. Science Advances. 2021 | AAAS

More publications

The Simmons lab investigates how biomechanical forces on cells lead to regeneration, repair, and disease of cardiovascular tissues. Our dynamic team of engineers, biomedical scientists, and physicists tackle applied biomedical problems in the areas of heart valve mechanobiology and disease, stem cell-based tissue regeneration, and microfluidic physiological systems. We are affiliated with the Department of Mechanical & Industrial Engineering and Institute of Biomaterials & Biomedical Engineering at the University of Toronto, and are core members of the Translational Biology & Engineering Program in the Ted Rogers Centre for Heart Research.

Recent News

More news

Recent Publications

  • Anthonyshyn Jeremy A., Mazzoli Vienna, McFadden Meghan J., Gramolini Anthony O., Hofer Stefan O. P., Simmons Craig A., Santerre, Paul. Mitigating the non-specific uptake of immunomagnetic microparticles enables the extraction of endothelium from human fat. Communications Biology. 2021 | Nature Publishing Group

    Continue reading →

  • Tang Mingyi, Eliathamby Daniella, Ouzounian Maral, Simmons Craig A, Chung Jennifer C.-Y. Dependency of energy loss on strain rate, strain magnitude and preload: Towards development of a novel biomarker for aortic aneurysm dissection risk. Journal of the Mechanical Behavior of Biomedical Materials. 2021 | Elsevier

    Continue reading →

  • Liu Haijao, Usprech Jenna F., Parameshwar Prabu K., Sun Yu, Simmons Craig A. Combinatorial screen of dynamic mechanical stimuli for predictive control of MSC mechano-responsiveness. Science Advances. 2021 | AAAS

    Continue reading →

More publications