The Simmons lab investigates how biomechanical forces on cells lead to regeneration, repair, and disease of cardiovascular tissues. Our dynamic team of engineers, biomedical scientists, and physicists tackle applied biomedical problems in the areas of heart valve mechanobiology and disease, stem cell-based tissue regeneration, and microfluidic physiological systems. We are affiliated with the Department of Mechanical & Industrial Engineering and Institute of Biomaterials & Biomedical Engineering at the University of Toronto, and are core members of the Translational Biology & Engineering Program in the Ted Rogers Centre for Heart Research.

Recent News

• Alisa wins top prize at the CRAFT Virtual Symposium 2021!
• Congratulations to Neda on the NSERC PDF!
• Congratulations to Mingyi & Daniella!

Recent Publications

• Dou Wenkun, Malhi Manpreet, Zhao Qili, Wang Li, Huang Zongjie, Law Junhui, Liu Na, Simmons Craig A., Maynes Jason T., Sun Yu. Microengineered platforms for characterizing the contractile function of in vitro cardiac models. 2022 | Springer Nature

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• Persson Henrik, Park Siwan, Mohan Michael, Cheung Ka Kit, Simmons Craig A., Young Edmond WK. Rapid assembly of PMMA microfluidic devices with PETE membranes for studying the endothelium. Sensors and Actuators B: Chemical. 2021 | Elsevier

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• McClarty Davis, Ouzounian Maral, Tang Mingyi, Eliathamby Daniella, Romero David, Nguyen Elsie, Simmons Craig A., Amon Cristina, Chung Jennifer C-Y. Ascending aortic aneurysm haemodynamics are associated with aortic wall biomechanical properties. European Journal of Cardio-Thoracic Surgery. 2021 | Oxford Academic

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