Overview
The Simmons lab investigates how biomechanical forces on cells lead to regeneration, repair, and disease of cardiovascular tissues. Our dynamic team of engineers, biomedical scientists, and physicists tackle applied biomedical problems in the areas of heart valve mechanobiology and disease, stem cell-based tissue regeneration, and microfluidic physiological systems. We are affiliated with the Department of Mechanical & Industrial Engineering and Institute of Biomaterials & Biomedical Engineering at the University of Toronto, and are core members of the Translational Biology & Engineering Program in the Ted Rogers Centre for Heart Research.

Recent News

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Recent Publications

  • Liu Haijao, Usprech Jenna F., Parameshwar Prabu K., Sun Yu, Simmons Craig A. Combinatorial screen of dynamic mechanical stimuli for predictive control of MSC mechano-responsiveness. Science Advances. 2021 | AAAS

  • Mirani Bahram, Parvin Nejad Shouka, Simmons Craig A. Recent progress toward clinical translation of tissue engineered heart valves. Canadian Journal of Cardiology. 2021 | Elsevier

  • Dou Wenkun, Wang Li, Malhi Manpreet, Liu Haijao, Zhao Qili, Plakhotnik Julia, Xu Zhensong, Huang Zongjie, Simmons Craig A., Maynes Jason T., Sun Yu. A microdevice platform for characterizing the effect of mechanical strain magnitudes on the maturation of iPSC-Cardiomyocytes. Biosensors and Bioelectronics. 2021 | Elsevier

More publications

The Simmons lab investigates how biomechanical forces on cells lead to regeneration, repair, and disease of cardiovascular tissues. Our dynamic team of engineers, biomedical scientists, and physicists tackle applied biomedical problems in the areas of heart valve mechanobiology and disease, stem cell-based tissue regeneration, and microfluidic physiological systems. We are affiliated with the Department of Mechanical & Industrial Engineering and Institute of Biomaterials & Biomedical Engineering at the University of Toronto, and are core members of the Translational Biology & Engineering Program in the Ted Rogers Centre for Heart Research.

Recent News

More news

Recent Publications

  • Liu Haijao, Usprech Jenna F., Parameshwar Prabu K., Sun Yu, Simmons Craig A. Combinatorial screen of dynamic mechanical stimuli for predictive control of MSC mechano-responsiveness. Science Advances. 2021 | AAAS

    Continue reading →

  • Mirani Bahram, Parvin Nejad Shouka, Simmons Craig A. Recent progress toward clinical translation of tissue engineered heart valves. Canadian Journal of Cardiology. 2021 | Elsevier

    Continue reading →

  • Dou Wenkun, Wang Li, Malhi Manpreet, Liu Haijao, Zhao Qili, Plakhotnik Julia, Xu Zhensong, Huang Zongjie, Simmons Craig A., Maynes Jason T., Sun Yu. A microdevice platform for characterizing the effect of mechanical strain magnitudes on the maturation of iPSC-Cardiomyocytes. Biosensors and Bioelectronics. 2021 | Elsevier

    Continue reading →

More publications