Overview
The Simmons lab investigates how biomechanical forces on cells lead to regeneration, repair, and disease of cardiovascular tissues. Our dynamic team of engineers, biomedical scientists, and physicists tackle applied biomedical problems in the areas of heart valve mechanobiology and disease, stem cell-based tissue regeneration, and microfluidic physiological systems. We are affiliated with the Department of Mechanical & Industrial Engineering and Institute of Biomaterials & Biomedical Engineering at the University of Toronto, and are core members of the Translational Biology & Engineering Program in the Ted Rogers Centre for Heart Research.

Recent News

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Recent Publications

  • Blaser MC, Wei K, Adams RLE, Zhou YQ, Caruso LL, Mirzaei Z, Lam AY, Tam RKK, Zhang H, Heximer SP, Henkelman RM, Simmons CA. Deficiency of Natriuretic Peptide Receptor 2 Promotes Bicuspid Aortic Valves, Aortic Valve Disease, Left Ventricular Dysfunction, and Ascending Aortic Dilatations in Mice. Circulation Research. 2018; 2(122): 405-416 | PubMed

  • Wong F. Jeremy, Young Edmond W.K, Simmons, Craig A. Computational analysis of integrated biosensing and shear flow in a microfluidic vascular model. AIP Advances. 2017; 7: 115116 | AIP

  • Zhang Xiaoqing, Battiston Kyle, Simmons Craig A, Santerre J Paul. Differential regulation of extracellular matrix components by using different vitamin C derivatives in mono-and co-culture systems. ACS Biomaterials Science & Engineering. 2017 | ACS

More publications

 

The Simmons lab investigates how biomechanical forces on cells lead to regeneration, repair, and disease of cardiovascular tissues. Our dynamic team of engineers, biomedical scientists, and physicists tackle applied biomedical problems in the areas of heart valve mechanobiology and disease, stem cell-based tissue regeneration, and microfluidic physiological systems. We are affiliated with the Department of Mechanical & Industrial Engineering and Institute of Biomaterials & Biomedical Engineering at the University of Toronto, and are core members of the Translational Biology & Engineering Program in the Ted Rogers Centre for Heart Research.

 

Recent News

More news

Recent Publications

  • Blaser MC, Wei K, Adams RLE, Zhou YQ, Caruso LL, Mirzaei Z, Lam AY, Tam RKK, Zhang H, Heximer SP, Henkelman RM, Simmons CA. Deficiency of Natriuretic Peptide Receptor 2 Promotes Bicuspid Aortic Valves, Aortic Valve Disease, Left Ventricular Dysfunction, and Ascending Aortic Dilatations in Mice. Circulation Research. 2018; 2(122): 405-416 | PubMed

  • Wong F. Jeremy, Young Edmond W.K, Simmons, Craig A. Computational analysis of integrated biosensing and shear flow in a microfluidic vascular model. AIP Advances. 2017; 7: 115116 | AIP

  • Zhang Xiaoqing, Battiston Kyle, Simmons Craig A, Santerre J Paul. Differential regulation of extracellular matrix components by using different vitamin C derivatives in mono-and co-culture systems. ACS Biomaterials Science & Engineering. 2017 | ACS

More publications