Shouka Parvin Nejad

Ph.D. Candidate
Institute of Biomaterials & Biomedical Engineering
Joined in 2013.

Research Keywords

  • Tetralogy of Fallot
  • Heart valve tissue engineering
  • Pulmonary valve
  • Human umbilical cord perivascular cells
  • Electrospun nanofibrous polycarbonate polyurethane

Contact Information
Office Tel: 416-978-6432

Research Summary

My research focuses on engineering valve tissue for the repair or replacement of the stenotic pulmonary valve in pediatric patients with Tetralogy of Fallot. Our goal is to produce an autologous valve-like tissue that can grow, repair, and remodel by culturing and conditioning mesenchymal stromal cells from the umbilical cord (human umbilical cord perivascular cells) on biodegradable electrospun polyurethane scaffolds.

Graphical Abstract

Recent News Publications
  • Mirani Bahram, Parvin Nejad Shouka, Simmons Craig A. Recent progress toward clinical translation of tissue engineered heart valves. Canadian Journal of Cardiology. 2021 | Elsevier

  • Parvin Nejad S, Blaser MC, Santerre JPS, Caldarone CA, Simmons CA. Biomechanical conditioning of tissue engineered heart valves: Too much of a good thing? Advanced Drug Delivery Reviews, 2016;96:161-75. | PubMed